2100 NE 52nd Street, Oklahoma City, OK Science Museum Oklahoma is located in the heart of Oklahoma City's Adventure District.
From Northeast OKC: I-35S, exit NE 50th, west on 50th
From Northwest OKC: I-44E, exit Martin Luther King, south to NE 50th
From West OKC: I-40E, exit I-35N, I-35N to NE 50th, west on 50th
From East OKC: I-40W, exit I-35N, north to NE 50th, west on 50th
From South OKC: I-35N, exit I-40E, exit I-35N, north to NE 50th, west on 50th